Guest stars appear throughout the show, with a number of the guest stars being faked with impersonators or random people (e.g.: Jerry Seinfeld, Russell Brand, George Clooney, The Hulk, Beyonce, Arnold Schwarzenegger [portrayed by Bruce Vilanch], and Jay-Z.)

• The Eric Andre Show - Season 1
• Eric André
• Hannibal Buress
• Tom Ato